Bills 49ers Prediction
Buffalo Bills vs San Francisco 49ers prediction, game preview, and fantasy player to watch.
Buffalo Bills vs San Francisco 49ers Broadcast
In our picks and predictions for Week 13 of the 2020 NFL season, the 49ers pull off another upset on 'Monday Night Football' and the Derrick Henry-Nick Chubb duel lives up to expectations. Buffalo Bills: Week 13 odds, lines and trends vs San Francisco 49ers by Jason Mattis. My final score prediction for this week is for the Bills to beat the 49ers 27-23. Fresh off a huge win over the Los Angeles Rams in Week 12, the San Francisco 49ers clash with the Buffalo Bills in the second game of a Monday Night Football doubleheader (Dec. 7, 8:15 pm EST). This contest will take place in Arizona, the Niners new home for the rest of the season, and has seen a pretty big line move at online sportsbooks. Buffalo Bills vs San Francisco 49ers Prediction, Line. Buffalo 27, San Francisco 24 Bet on Buffalo vs San Francisco with BetMGM San Francisco -1, o/u: 47 ATS Confidence out of 5: 2.5. Must See Rating: 3.5. 5: Gangs of London 1: Hillbilly Elegy. 49ers - Predictions. Score Prediction: San Francisco 24 Buffalo 21; Best Bet: 49ers PK; We get another Monday Night doubleheader this week thanks to all the scheduling changes this league has had recently, but the game that was always slated to be in this spot is the non-conference tilt between the Bills and 49ers.
Date: Sunday, December 7
Game Time: 8:15 ET
Venue: State Farm Stadium, Glendale, AZ
Network: ESPN and ABC
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Buffalo Bills (8-3) vs San Francisco 49ers (5-6) Game Preview
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Why Buffalo Bills Will Win
Buffalo has to start running, keep running, and don’t stop pounding.
There’s a turnover issue – more on that in a moment – and the offense works best when Josh Allen is balancing things out with his big shots down the field, but the San Francisco secondary is getting strong again, it’s fourth in the NFL in pass D, and it’s coming off a game when it made Jared Goff of the Rams look silly.
The Bills are 5-0 when running for over 100 yards, and control in this will matter. The Rams had some success on the ground, even if most of it came from one Cam Akers run. However …
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Why San Francisco 49ers Will Win
Buffalo can’t give the ball away.
San Francisco is too inconsistent with its big defensive plays, but when it makes them happen, forget it.
New England was able to run wild on the Niners, and lost big because of four turnovers. The same went for the Giants, who also ran well but lost big because of three giveaways. Last week? The Rams turned it over four times.
Buffalo has turned it over at least once in every game but two, and it screwed up five times over the last two games – losing to Arizona and beating the Chargers – with mistakes.
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Bills 49ers Prediction Green Bay Packers
RB Zack Moss, Buffalo
Can the Bills get steady production out of any of its backs? Devin Singletary has been fine at times, and Josh Allen is the most dangerous runner, but Moss has the best overall pop – now he needs the work. He ran for three touchdowns over a two-game stretch after coming off an injury, but that was it. He’ll get the ball around the goal line, but in this, feed him 15 times and watch what happens.
What’s Going To Happen
Yeah, Buffalo has had a turnover problem at times, but San Francisco has a bigger one with 13 over the last five games. The defense was able to pick up the slack against the Rams, but that won’t happen this week.
A “home” game for San Francisco in name only, it’s being played in Arizona, it’ll have a strange feel, and Buffalo will come out physical from the start as it runs for 150 yards, dominates on third downs, and is a +2 in turnover margin.
Buffalo Bills vs San Francisco 49ers Prediction, Line
Buffalo 27, San Francisco 24
Bet on Buffalo vs San Francisco with BetMGM
San Francisco -1, o/u: 47
ATS Confidence out of 5: 2.5
Must See Rating: 3.5
5: Gangs of London
1: Hillbilly Elegy
Bills 49ers Prediction Odds
The Buffalo Bills might be playing the Arizona 49ers on Monday Night Football next week.
According to NFL Network’s Ian Rapoport on Sunday, the 49ers (5-6) need to find a home away from home in San Francisco ahead of facing the Bills (8-3) next week and the likely spot is Arizona Cardinals’ home in Glendale.
Bills 49ers Prediction Action
Santa Clara County where the 49ers play has new COVID-19 restrictions. Those banned all contact sports and mandated a 14-day quarantine for anyone traveling into the area from 150 miles away.
So per reports, the answer appears to be State Farm Stadium in Arizona. In addition to Arizona, the answer could be in Texas as well, but Rap Sheet believes the answer will be Arizona.